Cutaneous adverse food reactions (CAFR) cause persistent dermatologic signs such as pruritus and erythema, often accompanied by gastrointestinal disturbances including diarrhea in dogs, making them a source of ongoing discomfort for both pets and owners (Valentine, 2020). Similar clinical patterns have been described in cats, where adverse food reactions may present with cutaneous signs and improve following dietary elimination and controlled feeding trials (Leistra & Willemse, 2002).
Clinical Indicators of Protein Sensitivity in Dogs and Cats
The diagnosis of CAFR is commonly based on an elimination diet trial followed by a provocative challenge (Tinsley et al., 2024). Research indicates that nonseasonal pruritus is the dominant clinical symptom, affecting approximately 94% of dogs with CAFR (Valentine, 2020). This commonly presents persistent scratching of the ears, paws, or ventral abdomen and may predispose affected dogs to secondary complications such as recurrent pyoderma or otitis externa (Valentine, 2020). Comparable dermatologic presentations have also been reported in cats with adverse food reactions, where pruritus and inflammatory skin lesions may improve following dietary elimination protocols (Leistra & Willemse, 2002; Bryan & Frank, 2010).
Beyond dermatological signs, gastrointestinal (GI) distress represents a frequent non-cutaneous manifestation. Clinical signs including diarrhea, vomiting, and increased defecation frequency are commonly observed in dogs with adverse food reactions (Valentine, 2020). Similar gastrointestinal involvement has been documented in feline patients, supporting the role of suspected dietary proteins as potential contributors to both cutaneous and enteric symptoms across species (Bryan & Frank, 2010). These presentations are often misattributed to environmental or infectious causes, which may delay appropriate nutritional evaluation.
Identifying Common Protein Allergens in Pet Food
Proteins commonly found in commercial pet foods, such as beef, chicken, and wheat, can lead to immune sensitization over time. Even minute quantities of these allergens can trigger a flare-up, with clinical relapse occurring rapidly following re-exposure, often within days, even at low amounts (Tinsley et al., 2024).
The Role of Novel Proteins and Elimination Diets
The "gold standard" for diagnosing CAFR remains the elimination diet trial, using either a hydrolyzed diet or a novel protein source—one to which the dog has had no prior exposure (Valentine, 2020). To achieve maximum diagnostic sensitivity, studies recommend an elimination trial duration of at least eight weeks, which allows over 90% of dogs to achieve remission of clinical signs (Valentine, 2020). Using a truly new protein reduces the likelihood of an immune response, allowing inflammation in the skin and gastrointestinal tract to subside (Roudebush et al., 2010).
Kangaroo as a Hypoallergenic Reset
Kangaroo is considered an ideal novel protein because it is rarely encountered in standard commercial diets, making it an effective immune rest through antigen avoidance for the immune system. Addiction Pet Foods utilizes wild-harvested Australian kangaroo to provide high-quality, hypoallergenic options:
• Nutritional Profile: Kangaroo meat is naturally lean and provides essential minerals such as iron and zinc, which are important for normal metabolic and skin functions
• Addiction Wild Kangaroo & Apples: A grain-free dry formula that excludes common allergens such as beef, chicken, wheat, corn, and soy, utilizing pectin-rich apples for fiber.
• Addiction Outback Kangaroo Feast: A raw-alternative muscle-meat recipe enriched with nutrient-dense superfoods like papayas and blueberries to support digestion and skin health.
• Addiction Kangaroo Recipe Meaty Bites: Single-protein, grain-free treats designed for training rewards without compromising a sensitive dog's diet.
• Addiction Wild Kangaroo Feast (Cat Food): Limited-ingredient, grain-free, single-protein recipe made with wild kangaroo as the only animal protein, formulated to support sensitive skin and digestion in cats prone to food sensitivities.
Implementation and Transition
Transitioning a dog with sensitivities to a novel protein requires a gradual protocol to avoid acute GI upset. A 7 to10-day transition period is recommended, starting with a ratio of 25% new food to 75% old food, and increasing the new protein every few days. This allows the digestive system to adapt while the owner and clinician monitor for a reduction in pruritus and GI symptoms (Tinsley et al., 2024).
By utilizing ethically sourced, nutrient-dense novel proteins, owners can effectively manage chronic sensitivities and restore their pet's vitality. Disclosure: This content is provided by Addiction Pet Foods for educational purposes. Product examples are included to illustrate nutritional approaches and should be used in consultation with a veterinarian.
References
Bryan, J., & Frank, L. A. (2010). Food allergy in the cat: A diagnosis by elimination. Journal of Feline Medicine and Surgery, 12(11), 861–866. https://doi.org/10.1016/j.jfms.2010.09.003
Leistra, M., & Willemse, T. (2002). Double-blind evaluation of two commercial hypoallergenic diets in cats with adverse food reactions. Journal of Feline Medicine and Surgery, 4(4), 185–188. https://doi.org/10.1053/jfms.2002.0209
Roudebush, P., Guilford, W. G., & Shanley, K. J. (2010). Adverse reactions to food. In M. S. Hand, C. D. Thatcher, R. L. Remillard, P. Roudebush, & B. J. Novotny (Eds.), Small animal clinical nutrition (5th ed., pp. 609–635). Mark Morris Institute.
Tinsley, J., Griffin, C., Sheinberg, G., Griffin, J., Cross, E., Gagné, J., & Romero, A. (2024). An open-label clinical trial to evaluate the efficacy of an elemental diet for the diagnosis of adverse food reactions in dogs. Veterinary Dermatology, 35(1), 40–50. https://doi.org/10.1111/vde.13198
Valentine, B. (2020). Review of critically appraised topics on adverse food reactions of companion animals. Canadian Veterinary Journal, 61(5), 537–539.